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Plot Power Vs Sample Size
Use the graphing tools to explore and compare your adaptive trial design. Then easily share your conclusions with all trial stakeholders.
In the specify multiple factors tool you can enter one or more values for each of the assumptions required in that table. If you enter multiple values for a particular assumption then each of these will be used in the table above and if this is done for more than one assumption then all combinations of all the values will be included in the main table.
For example, in the two sample t-test we can see the effect of changing anything from the significance level to the standard deviation on any of the solvers in the table which in this table would be for; the effect size, sample size or power.
盲估计样本量 如果与中间值相比,研究前方差被低估,则增加样本量
无盲样本量重估计 定义中间分析是否“可信”
分组序贯试验 为了有效性/无用性而提前停止
条件把握度 一种频率分析法,给出在研究结束时达到统计显著性的概率,给出在中期分析之前获得的数据
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